Disability UK Online Health Journal - All In One Business In A Box - Forum - Business Directory - Useful Resources

Category: Heart failure

Study Reveals Link Between Breakdown Product from Excessive Niacin and Heart Disease

Study Reveals Link Between Breakdown Product from Excessive Niacin and Heart Disease

Introduction: Niacin, also known as vitamin B3, has long been hailed for its potential health benefits, particularly in supporting cardiovascular health. However, recent research has shed light on a potential downside to excessive niacin intake. A groundbreaking study has unearthed a connection between a breakdown product of niacin and an increased risk of heart disease. This discovery underscores the importance of moderation and balanced supplementation when it comes to vitamins and nutrients.

The Study: The study, conducted by a team of researchers from renowned institutions, including universities and medical centers, analyzed data from a large population cohort. The researchers focused on the metabolism of niacin within the body and its potential implications for cardiovascular health. Their findings, published in a leading medical journal, revealed a concerning association between a metabolite of niacin and the development of heart disease.

Breakdown Product and Heart Disease Risk: Niacin is metabolized in the body into various byproducts, one of which is nicotinamide N-methyltransferase (NNMT). While NNMT has been previously studied in relation to metabolism and inflammation, its connection to heart disease was not well understood until now. The researchers found that elevated levels of NNMT were associated with an increased risk of developing heart disease, including conditions such as atherosclerosis and coronary artery disease.

Mechanism of Action: The exact mechanism through which NNMT contributes to heart disease is still under investigation. However, researchers propose several potential pathways. One possibility is that NNMT may promote inflammation within the arterial walls, leading to the formation of plaques and the narrowing of blood vessels. Additionally, NNMT could influence lipid metabolism, altering cholesterol levels and contributing to the buildup of plaque in the arteries.

Implications for Niacin Supplementation: Niacin supplements have been widely used for their purported benefits in managing cholesterol levels and supporting heart health. However, this study suggests that excessive niacin intake could inadvertently increase the risk of heart disease through the production of NNMT. While niacin is an essential nutrient, it is crucial for individuals to exercise caution and moderation when supplementing with high doses.

Balanced Approach to Nutrition: This study underscores the importance of adopting a balanced approach to nutrition and supplementation. While certain nutrients may offer health benefits, excessive intake or imbalance can have unintended consequences. Instead of relying solely on supplements, individuals are encouraged to prioritize a varied diet rich in whole foods, including fruits, vegetables, whole grains, lean proteins, and healthy fats.

Consultation with Healthcare Professionals: Before initiating any supplementation regimen, individuals should consult with their healthcare providers, particularly if they have existing health conditions or are taking medications. Healthcare professionals can provide personalized guidance based on individual health status, ensuring that any supplements are used safely and effectively.

Future Research Directions: Further research is needed to elucidate the precise role of NNMT in the development of heart disease and to explore potential therapeutic interventions. Additionally, studies examining the effects of niacin supplementation on cardiovascular health should take into account the metabolism of niacin and its byproducts.

Conclusion: The link between a breakdown product from excessive niacin intake and heart disease uncovered by this study highlights the complexity of nutritional science. While niacin remains an important nutrient with potential health benefits, moderation is key. Individuals should strive for a balanced approach to nutrition, focusing on whole foods and consulting with healthcare professionals before supplementing with high doses of any nutrient. By prioritizing informed decision-making and ongoing research, we can better understand the intricate relationship between nutrients and health outcomes, ultimately promoting cardiovascular wellness for all.

Study discovers link between a breakdown product from excess niacin and heart disease (msn.com)

#heartdisease ##naicin #supplements #cardiovascular #healthcare #nutrients #nutrition #diet #nnmt #vitamins

Disability UK Content Writing Services Logo

Guest Writers Needed – On Health!

Empty Canvas
Content Coming Soon!


Boots Logo


We are in the process of building our own directory of A-Z illnesses and disabilities. If you happen to land on this page we encourage you to visit the NHS website about the topic in our category.

Awaiting Content On Health!

It is vital to have platforms that champion inclusivity and diversity, bringing stories and experiences from all walks of life to the forefront. The Disabled Entrepreneur – Disability UK Online Journal is one such platform dedicated to representing the experiences, insights, and accomplishments of disabled individuals. However, like an empty canvas waiting for an artist’s brush, our pages are currently awaiting content. We’re excited to invite guest writers to share their knowledge and perspectives on all health topics, from A to Z. If you have landed on this page that means the category needs content.

A Platform for the Disabled Community

The Disabled Entrepreneur – Disability UK Online Journal is more than just a publication; it’s a celebration of resilience, innovation, and success in the face of adversity. Disabled entrepreneurs, activists, healthcare professionals, and advocates have a valuable platform to share their insights and experiences. This journal is a space where stories and knowledge intersect to form a resource-rich hub for the entire disabled community.

Why Your Contribution Matters

Sharing your expertise and experiences on this platform can have a profound impact in several ways:

  1. Inspiration and Representation: Your stories and knowledge can inspire others in the disabled community. Representation matters, and your contribution can pave the way for others to follow in your footsteps.
  2. Education: The world of disabilities is vast and diverse. By contributing to the journal, you can educate the public and offer insights into topics such as disability rights, accessible technology, healthcare, adaptive sports, and more.
  3. Fostering Inclusivity: By sharing your perspective, you help break down barriers and stigmas surrounding disabilities. The more we understand each other, the more inclusive our society can become.
  4. Professional Growth: Becoming a guest writer for a reputable platform like this can enhance your professional profile and provide valuable networking opportunities.

Topics We’re Looking For

At the Disabled Entrepreneur – Disability UK Online Journal, we aim to cover a wide range of health topics and disability-related subjects. Our pages are open to contributions that span the A to Z of health and disability, including but not limited to:

  • Accessible Technology: Innovations in assistive devices and technology.
  • Mental Health: Strategies for managing mental health while navigating life with a disability.
  • Policy and Advocacy: Insights into disability rights and policy changes.
  • Entrepreneurship and Business: Stories of successful disabled entrepreneurs and startup guidance.
  • Inclusive Education: Strategies for creating inclusive learning environments.
  • Wellness and Healthcare: Tips on maintaining physical and mental health.

Browse our categories to see what content we need.

If you’re interested in sharing your knowledge, experiences, or insights on disability-related topics, we invite you to become a guest writer for the Disabled Entrepreneur – Disability UK Online Journal. To get started, simply follow these steps:

  1. Pitch Your Idea: Send us a brief pitch outlining your proposed topic to [email address]. Ensure that it aligns with our vision and mission.
  2. Write Your Article: Once your pitch is approved, start working on your article. Our editorial team will be available to provide guidance and feedback.
  3. Submit Your Article: When your article is ready, submit it for review.
  4. Engage with Our Community: We encourage our guest writers to engage with our readers through comments and discussions, offering valuable insights and answering questions.


The Disabled Entrepreneur – Disability UK Online Journal is not just a publication; it’s a collective voice that celebrates the achievements and experiences of the disabled community. We believe in the power of collective knowledge, and we invite you to be a part of our mission. Your contribution can be a stepping stone for others and an invaluable resource for the world. Join us in filling our pages with content that resonates, educates, and inspires.

As a guest writer, you’ll gain exposure and the chance to build a portfolio of content. We also offer backlinks to your personal or professional website, enhancing your online presence. By sharing your knowledge with our community, you’re not only enriching our journal but also empowering individuals within the disabled community and beyond.

At Disabled Entrepreneur – Disability UK, we are committed to supporting our talented writers. Our goal is to create a platform that compensates contributors once we reach a level of traffic that sustains such payments. As we grow, we are exploring the possibility of introducing a paywall system. This approach will help us continue to provide quality content while rewarding our dedicated writers for their valuable contributions. Your words and expertise are an essential part of our journey, and we look forward to a future where we can reciprocate your efforts more substantially.

#guestposts #guestwriting #articlewriting #backlinks #portfoliobuilding #illnesses #disabilities #disabledentrepreneur.


Boots Logo


UK Banner



Blue Butterfly Logo